Australian Public Assessment Report for Budesonide/eformoterol fumarate dihydrate
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Early asthma control and maintenance with eformoterol following reduction of inhaled corticosteroid dose.
BACKGROUND Previous studies have indicated the benefits of adding long acting beta(2) agonists to inhaled corticosteroids in the maintenance treatment of moderate to severe asthma. The effects of adding eformoterol to corticosteroids on asthma control and exacerbations in patients with mild to moderate asthma were studied. METHODS After a run in period of 7-14 days on existing medication, 663...
متن کاملThe Potential For Improved Inhalation Technique With Duoresp® Spiromax® (Budesonide + Formoterol Fumarate Dihydrate) Compared With Commonly Prescribed Dry Powder Inhalers For The Management Of Asthma And Chronic Obstructive Pulmonary Disease In Spain: Estimated Impact On Number And Cost Of Unscheduled Healthcare Events.
• Asthma and chronic obstructive pulmonary disease (COPD) are common respiratory conditions that represent a considerable cost burden to the Spanish healthcare system1. • Symbicort® Turbuhaler® (budesonide + formoterol fumarate dihydrate) and Seretide® Accuhaler® (fluticasone propionate + salmeterol) are commonly used dry powder inhalers (DPIs) in Spain, and can be difficult for patients to tra...
متن کاملEquivalent Lung Dose and Systemic Exposure of Budesonide/Formoterol Combination via Easyhaler and Turbuhaler
BACKGROUND Easyhaler(®) device-metered dry powder inhaler containing budesonide and formoterol fumarate dihydrate (hereafter formoterol) for the treatment of asthma and chronic obstructive pulmonary disease has been developed. The current approvals of the product in Europe were based on several pharmacokinetic (PK) bioequivalence (BE) studies, and in vitro-in vivo correlation (IVIVC) modeling. ...
متن کاملCost-effectiveness of eformoterol Turbohaler versus salmeterol Accuhaler in children with symptomatic asthma.
We conducted an economic evaluation in a UK setting based on a 12-week prospective randomized open-label parallel-group comparison of eformoterol Turbohaler 12 microg b. i.d. with salmeterol Accuhaler 50 microg b. i.d. in children aged 6-17 with symptomatic asthma receiving inhaled corticosteroids and short-acting beta2-agonists. The principal effectiveness measure was percentage of symptom-fre...
متن کاملA dose-response study with formoterol Turbuhaler as maintenance therapy in asthmatic patients.
The aim of this randomized, double-blind, parallel group study was to determine the lowest effective dose of 6, 12 and 24 microg formoterol fumarate dihydrate Turbuhaler b.i.d. compared with placebo. The 4 week treatment was preceded by a 1 week run-in period. Morning peak expiratory flow (PEF) before intake of the study drug was the primary variable. Patients recorded PEF, prior to and 15 min ...
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تاریخ انتشار 2010